The recent findings surrounding osimertinib (Tagrisso) in patients with EGFR-mutated non-small cell lung cancer (NSCLC) from both the LAURA and ADAURA trials have sparked excitement in the medical community. Dr. Roy Herbst, from Yale Cancer Center in New Haven, Connecticut, discusses the improvements in progression-free survival (PFS) in stage III patients and the potential of
Health
An analysis of medical records involving over 88,000 systemic lupus erythematosus (SLE) patients has revealed promising results for those taking metformin. The research conducted by Yurilu A. Gonzalez Moret, MD, and colleagues at Thomas Jefferson University suggests that individuals with SLE who are on metformin are at a lower risk of developing lupus nephritis, chronic
Patients diagnosed with rheumatoid arthritis (RA) often face a heightened risk of cardiovascular events and mortality. Traditional risk factors such as smoking, obesity, and hypertension do not fully account for the increased cardiovascular risk observed in RA patients. This has led researchers to explore additional biomarkers that could help predict major adverse cardiovascular events (MACE)
A recent study has shed light on the missed opportunities in treating drug overdose survivors under the Medicare program. It highlighted the challenges of managing chronic pain in this vulnerable population. Despite recommendations from experts to prioritize comprehensive treatment for overdose survivors, the reality is quite different. The study found that a significant number of
The approval of PD-1-directed immune checkpoint inhibitor pembrolizumab in combination with carboplatin and paclitaxel is a significant advancement for patients with primary advanced or recurrent endometrial cancer. The results of the KEYNOTE-868/NRG-GY018 trial showed that patients with either mismatch repair (MMR)-deficient or MMR-proficient disease benefited from this immunotherapy-chemotherapy combination. In the trial, the addition of
Dean Ornish, MD, believes that an intensive lifestyle intervention could potentially slow down the progression of early Alzheimer’s disease. This is a groundbreaking approach that challenges traditional methods of treatment for the condition. However, while the idea of “good” side effects is promising, it is important to approach such interventions with caution and further research
In a recent study presented at the European Alliance of Associations for Rheumatology (EULAR) annual meeting, the efficacy of patient-initiated follow-up contacts versus clinician-monitored follow-up for patients with axial spondyloarthritis (axSpA) was examined. This study, conducted by Inger Jorid Berg, MD, PhD, emphasized the potential benefits of letting patients take the lead in managing their
Air pollution is a growing concern not only for the environment but also for human health, especially for pregnant women. Recent studies have brought to light the troubling connection between maternal exposure to particulate matter (PM) and adverse outcomes during pregnancy, particularly relating to blood pressure issues. It is crucial to address this hidden risk
The advancement in research for the treatment of EGFR-mutant non-small cell lung cancer is crucial in improving patient outcomes. In a recent study conducted by Erminia Massarelli, MD, PhD, the combination of osimertinib and consolidative stereotactic ablative radiation (SABR) showed promising results. The study involved 43 patients with untreated EGFR-mutant non-small cell lung cancer with
A recent incident involving a woman who developed hives all over her body after breastfeeding her newborn son has shed light on a rare and unusual condition known as lactation anaphylaxis. The woman took to social media to share her story, revealing that she was diagnosed with this condition after experiencing hives and a headache