Respiratory syncytial virus (RSV) is a common respiratory virus that can be serious for older adults, particularly those aged 60 and older. The CDC’s Advisory Committee on Immunization Practices (ACIP) has emphasized the benefits of vaccination against RSV in this age group, despite the small risk of vaccine-related Guillain-Barré syndrome (GBS). Evaluating the Risk of
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In a recent randomized phase II trial, Barzolvolimab, an anti-KIT monoclonal antibody, has shown promise in reducing the severity of hives in adults with chronic spontaneous urticaria (CSU) who have not seen relief with antihistamines. The study, presented at the American Academy of Allergy, Asthma & Immunology annual meeting, demonstrated significant improvements in the 7-day
A retrospective cohort study conducted by Maggie L. DiNome, MD, and colleagues from Duke University School of Medicine revealed significant variations in the odds of achieving pathologic complete response (pCR) and improved overall survival (OS) among patients with triple-negative breast cancer (TNBC) who underwent neoadjuvant chemotherapy. The study found that Black women with TNBC were
The World Health Organization (WHO) has recently updated its infection prevention and control (IPC) guideline for Ebola and Marburg disease in an effort to tackle “inappropriate practices” in managing these outbreaks. This includes revisiting existing recommendations based on past experiences with outbreaks of these deadly diseases. According to a summary of the recommendations by Victoria
The disparity in life expectancy within cities like Washington, D.C. is truly staggering. The fact that individuals living just a few miles apart can have a difference in life expectancy of more than a decade is a stark reminder of the inequalities that exist in our society. These disparities are not unique to Washington, D.C.,
A recent study conducted by Irene Xin-Yin Wu, PhD, and colleagues at Central South University in Hunan, China, explored the impact of adherence to healthy lifestyle behaviors on the incidence of irritable bowel syndrome (IBS) among a large cohort of individuals over a 12.6-year follow-up period. The findings revealed a significant association between healthy lifestyle
An analysis conducted by Pieter Cohen, MD, and colleagues at Cambridge Health Alliance revealed significant variations in the quantity and quality of galantamine sold as dietary supplements versus generic drugs. The study found that the actual amount of galantamine in dietary supplements ranged from 2% to 110% of the labeled quantity, whereas generic drugs contained
A recent phase III trial conducted in China revealed that a three-dose vaccine regimen known as HEV239 has shown high efficacy in preventing hepatitis E virus (HEV) infections over a 10-year period. The study, led by Shoujie Huang, MSc, from Jiangsu Provincial Centre for Disease Control and Prevention, reported an efficacy rate of 83.1% in
The American Gastroenterological Association (AGA) has recently endorsed the use of fecal microbiota-based therapies for recurrent Clostridioides difficile infections (CDIs) in new guideline recommendations. However, they have advised against the use of such therapies for inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). These recommendations were made by a guideline panel consisting of experts
The study comparing various screening scenarios, including annual screening at ages 40 to 79, revealed that this particular age range resulted in the greatest reduction in mortality. According to Debra L. Monticciolo, MD, and colleagues from Dartmouth-Hitchcock Medical Center, mortality was reduced by 41.7% with annual screening starting at age 40 and continuing up to