Health

The opioid epidemic in the United States has been greatly influenced by the rise of fentanyl in the drug supply. As a result, the treatment of opioid use disorder (OUD) with medications like buprenorphine and methadone has become increasingly complex. Despite years of data and experience with fentanyl, dosing guidelines for these medications have not

Metastatic uveal melanoma, though rare, is a significant health concern, and finding effective treatment options for this disease has been challenging. However, updated results from a phase III trial demonstrated a significant survival benefit with the bispecific T-cell receptor therapy tebentafusp (Kimmtrak) for selected patients with previously untreated metastatic uveal melanoma. These findings provide hope

A recent prospective study presented at the American Society for Reproductive Medicine (ASRM) annual meeting has found that midlife women with untreated and new-onset hypertension face an increased risk of developing fibroids. Contrarily, women already receiving treatment for hypertension, especially those using an angiotensin-converting enzyme (ACE) inhibitor, have a lower risk of fibroid diagnosis. The

The Advancing American Kidney Health Initiative has set a national priority of reducing end-stage renal disease (ESRD). To achieve this goal, it is crucial to focus on dialysis-requiring acute kidney injury (AKI-D), as it accounts for over 15% of patients starting dialysis at outpatient hemodialysis units. While the prevalence of AKI-D patients in these units

Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by the destruction of insulin-producing beta-cells. The search for effective treatments to preserve beta-cell function and delay disease progression has been ongoing for years. Recently, the PROTECT trial evaluated the efficacy of teplizumab (Tzield), a novel therapeutic agent, in early T1D. This article aims to

The landscape of HIV treatment is constantly evolving, with new options becoming available to both providers and patients. One such option that has garnered attention is long-acting injectable antiretroviral therapy (ART). While it offers a promising alternative to oral medications, the limitations and challenges surrounding its use cannot be ignored. In this article, we will

Critically ill patients often require blood transfusions to improve their chances of survival. However, determining the appropriate amount of blood to transfuse is a challenging task for healthcare providers. Janet Adegboye, MD, from Johns Hopkins University, conducted a retrospective analysis to investigate the relationship between hemoglobin levels and in-hospital mortality in massively transfused patients. The

Multiple sclerosis (MS) has long been a challenging condition for both patients and medical professionals. However, there is growing optimism within the field as a path to a cure appears to be on the horizon. In a keynote speech at the joint meeting of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS)

Patients with a penicillin allergy often face limited options for antibiotic treatment, which can sometimes be life-threatening. However, recent research suggests that many patients may be inaccurately labeled as allergic to penicillin. In a quality-improvement project conducted at a community hospital, Ibrahim Shah, MD, and his colleagues aimed to delabel patients with a penicillin allergy

Breast cancer is a devastating disease that affects millions of women worldwide. In recent years, there have been significant advancements in the treatment and management of breast cancer. One such development is the PREDICT prognostication tool, a web-based tool that estimates the risk of dying from breast cancer and the potential benefits of different adjuvant