The U.S. Food and Drug Administration (FDA) has granted approval for Eplontersen (Wainua) as a treatment option for polyneuropathy associated with hereditary transthyretin-mediated amyloidosis (ATTR). This significant development was jointly announced by Ionis Pharmaceuticals and AstraZeneca. ATTR-PN, which affects a global population of around 30,000 to 40,000 individuals, occurs due to a mutation in the
Health
The field of cancer research and treatment is constantly evolving, with new advancements and studies being conducted regularly. In this article, we will critically analyze recent developments and findings in the world of oncology. One interesting study conducted by Penn Medicine and published in the American Journal of Preventive Medicine highlighted the importance of patient
The FDA has recently expanded the age range for EndeavorRx, a prescription video game treatment for Attention-Deficit/Hyperactivity Disorder (ADHD). The maker of the game, Akili, announced that it is now approved for use in adolescents aged 13 to 17, in addition to its previous approval for children aged 8 to 12. This expansion opens up
Ozanimod, a sphingosine-1-phosphate (S1P) receptor modulator, has long been associated with warnings against its usage during pregnancy due to potential complications. However, a recent study presented at the Advances in Inflammatory Bowel Diseases annual meeting challenges this notion. The study examined the pregnancy outcomes of women with inflammatory bowel disease (IBD) and relapsing multiple sclerosis
Women who have previously undergone a cesarean section face a challenging decision when considering their mode of delivery for subsequent pregnancies. While planning another cesarean delivery may carry a higher risk of maternal complications, attempting vaginal delivery is associated with increased risks of uterine rupture and perinatal complications. To address this dilemma, the Canadian PRISMA
In 2003, two political leaders with opposing views in the U.S. Senate joined forces to support President George W. Bush in authorizing the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR). This groundbreaking program was a response to the spiraling global AIDS crisis and aimed at saving lives above political differences. Fast forward to today,
Being thrust into an impoverished rural area of Iran as a young physician, I was faced with daily challenges that tested my resilience and strength. However, amidst the difficulties, I found solace in storytelling. Writing became my survival mechanism, a way to make sense of the chaos around me and to share the experiences that
The recent FDA approval of zuranolone, a pill specifically designed to treat postpartum depression (PPD), is undoubtedly a significant scientific achievement. With two successful phase III trials, zuranolone joins the IV infused brexanolone as the only approved psychopharmacological treatments for PPD. The development of these drugs, which target allopregnanolone and modulate the GABAA receptor, not
The use of sterile gloves when treating wounds has long been considered a standard practice to prevent infections. However, a recent meta-analysis of randomized trials is challenging this notion. According to the pooled results of four randomized controlled trials (RCTs), there is no significant difference in the risk of surgical site infections when using sterile
The Centers for Medicare & Medicaid Services (CMS) recently announced that health spending in the U.S. reached a staggering $4.5 trillion in 2022, representing a 4.1% increase from the previous year. While this growth is higher than the 3.2% increase observed in 2021, it falls significantly short of the remarkable 10.6% growth experienced in 2020.