Colorectal cancer (CRC) is a significant health concern, and routine screening is recommended for individuals between the ages of 45 and 75. However, the benefits and risks of screening can vary depending on a patient’s age, health status, and previous screening history. In a recent cluster randomized trial involving U.S. veterans, researchers sought to determine
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The development of eosinophilic esophagitis (EoE) later in childhood has been linked to antibiotic and acid suppressant exposure during the perinatal period, according to a Danish cohort study. The study found that infants with any antibiotic use had a 40% greater risk of developing EoE compared to controls without such exposure. Additionally, maternal antibiotic use
The COVID-19 pandemic has taken a toll not only on the physical health of individuals worldwide but also on the mental and emotional well-being of healthcare workers. The relentless battle against the virus, coupled with the overwhelming demands of an already strained healthcare system, has led to skyrocketing rates of burnout among these frontline heroes.
As I enter the room for my weekly clinical trial visit, I am met with tired smiles from my home-based participants. These patients, who suffer from transthyretin-mediated amyloidosis, a progressive and fatal condition, eagerly participate in a clinical trial for a new drug. Despite not directly benefiting from the research themselves, they hope that their
In a recent prospective observational cohort study, the use of misoprostol alone was found to be effective in self-managed abortion, with minimal side effects. The study involved callers from safe abortion hotlines in Nigeria, Argentina, and Southeast Asia. The findings shed light on the acceptability and effectiveness of this method, suggesting that misoprostol alone could
In a retrospective study conducted at an Arkansas hospital, it was found that Black children had a significantly higher risk of dying from sepsis compared to their white counterparts, despite similar clinical responses. The study, led by Michele Moss from the University of Arkansas for Medical Sciences College of Medicine, focused on over 3,500 pediatric
As the COVID-19 pandemic continues to challenge healthcare systems worldwide, researchers have been exploring various treatment options to improve patient outcomes. One such potential treatment that garnered interest was intravenous vitamin C. However, two harmonized clinical trials, LOVIT-COVID and REMAP-CAP, revealed that intravenous vitamin C did not significantly increase the number of days patients were
Huntington’s disease is a devastating neurodegenerative disorder that results in progressive motor, psychiatric, and cognitive decline. Currently, there are no effective treatments to stop or reverse the symptoms. However, a recent study conducted by Melissa Scholefield and her colleagues at the University of Manchester has shed light on the potential role of metal levels in
The American College of Emergency Physicians (ACEP) has recently made a significant decision to discontinue the use of the term “excited delirium” when referring to patients with hyperactive delirium. This move aligns ACEP with other medical societies that have already abandoned the controversial term. This groundbreaking shift in perspective reflects an evolving understanding of hyperactive
The opioid epidemic in the United States has been greatly influenced by the rise of fentanyl in the drug supply. As a result, the treatment of opioid use disorder (OUD) with medications like buprenorphine and methadone has become increasingly complex. Despite years of data and experience with fentanyl, dosing guidelines for these medications have not