Chronic kidney disease (CKD) is a complex condition that can lead to a variety of serious complications, including gastrointestinal (GI) bleeding. A recent retrospective study presented by Mingyue He, MD, at the National Kidney Foundation (NKF) Spring Clinical meeting revealed that individuals with advanced CKD, particularly those in stage 5, faced a significantly higher risk of hospitalization due to GI bleeding. The odds ratio for hospitalization with GI bleeding in patients with stage 5 CKD was 1.4 (95% CI 1.3-1.4, P